High-altitude-related pulmonary disease is a spectrum of acute and chronic illnesses with a well-described epidemiology.

The risk for these illnesses is related to well-known environmental risk factors and lesser-known but important genetic factors. Prevention of acute high-altitude illness is possible in most visitors from lower elevations. Chronic high-altitude illnesses have an important worldwide impact.

Maloney, J.P., Broeckel, U. (2005). Clinical in Chest Medicine. 26, 3, 395-404.

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